Tuesday, February 8, 2011



Generic Name:
Ceftriaxone Na
Ceftriaxone Sodium

Brand Name:
Rocephin

Available Forms:
Infusion: 1g, 2g piggyback; 1g, 1g/ 50ml premixed

Injection: 250mg, 500mg, 1g, 2g

Dosage, Frequency and Route:
Adult:
750mg-1.5g IM/IV every 6-8 hrs. for 5-10 days.

Action:
3rd Generation Cephalosporin; Antibiotic

Inhibit cell wall synthesis, promoting osmotic instability: usually bactericidal.

Antibiotic, periop prophylaxis of infections

Side Effects:
GI upset, headache, dizziness, nausea & vomiting

Contraindications:
Contraindicated to patient hypersensitivity to cephalosporin.

Use cautiously in patients hypersensitive to penicillin because of possibility of cross-sensitivity with other beta-lactam antibiotics.

Nursing Considerations:
• Before administration, ask patient if he/she is allergic to penicillins or cephalosporins.

• Obtain specimen for culture and sensitivity tests before giving first dose.

• For IM administration, inject deep into a large muscle, such as the gluteus maximus or the lateral aspect of the thigh.

• If large doses are given, therapy is prolonged or patient is at high risk, monitor patient for signs and symptoms of superinfection.

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